Description

Neurofilament L, a subunit of neurofilaments (Nfs), is a cylindrical protein located in the cytoplasm of neurons. Neurofilaments play an important role in the structural stability of neurons, which are present in dendrites, axons and neuronal bodies. Only a small amount of NfL is released under normal circumstances. However, when the nervous system is damaged by inflammation, trauma or neurodegeneration, the release of NfL will increase dramatically. It can be spread through the CSF to blood, body fluids, the content of the NfL and neurologic injury is closely related to the disease. Therefore, NfL is also used as a diagnostic marker for neuronal injury diseases.

HKIG innovative products: Neurofilament L antigen. The protein was expressed in mammalian cells and prepared, covering the full length of the protein with high purity, maintaining the native protein conformation to the maximum extent and close to the natural protein structure in the physiological state, which is helpful for the accurate quantitative detection of related indicators.

1. Purity
   >90% by SDS-PAGE