Description
Pepsinogen (PG) is a single-chain polypeptide composed of 375 amino acids that belongs to the aspartate protein family. Human pepsinogen can be divided into seven isoenzymes, of which pg1-pg5 has common immunogenicity, known as PG I; pg6 to pg7 has a slower migration rate and is called PG II. The change of serum PG level is a clinical indicator of gastric cancer and gastric mucosal carcinoma. The lower the ratio of serum PG I to PG II, the higher the incidence of gastric cancer occurs [1].
HKIG offers two monoclonal antibodies for PG II detection (1014101 and 1014201).
Anti PG II monoclonal antibody
Catalog No. | Kaff | Subtype | Pairing | Application |
1014101 | >109 | Mouse IgG1/κ | Cap. | CLIA, ELISA |
1014201 | >109 | Mouse IgG1/κ | Det. | CLIA, ELISA |
Reference:
【1】Journal of Gastroenterological Mass Survey, 1994, 32(3):21-27.