Description

Pepsinogen (PG) is a single-chain polypeptide composed of 375 amino acids that belongs to the aspartate protein family. Human pepsinogen can be divided into seven isoenzymes, of which pg1-pg5 has common immunogenicity, known as PG I; pg6 to pg7 has a slower migration rate and is called PG II. The change of serum PG level is a clinical indicator of gastric cancer and gastric mucosal carcinoma. The lower the ratio of serum PG I to PG II, the higher the incidence of gastric cancer occurs ^[1].

HKIG offers two monoclonal antibodies for PG II detection (1014101 and 1014201).

Anti PG II monoclonal antibody

Reference：

【1】Journal of Gastroenterological Mass Survey, 1994, 32(3):21-27.