Description
Cancer antigen 125 (carbohydrate antigen 125, CA125) is a glycoprotein of the mucin family, named mucin 16 (MUC-16). CA125 is derived from body cavity epithelial cells and is a well-known biomarker for the differential diagnosis of epithelial ovarian cancer and pelvic masses [1]. CA125 was originally named by the Oc125 monoclonal antibody, and CA125-specific antibodies are classified into several families according to their different binding characteristics [2].
HKIG currently offers 2 paired monoclonal antibodies for the detection of human CA125 (catalog numbers: 1002101, 1002201).
Anti CA125 monoclonal antibody
| Catalog No. | Kaff | Subtype | Pairing | Application |
| 1002101 | >109 | Mouse IgG1/κ | Cap. | CLIA, ELISA |
| 1002201 | >109 | Mouse IgG1/κ | Det. | CLIA, ELISA |
Example of CA125 standard curve (CLIA).
Capture antibody: 1002101, Detection antibody: 1002201. R2>0.99 LoB<0.5U/mL
Reference：
【1】Int J Gynecol Cancer. 2005; 15:679–691.
【2】Molecular Cancer 2014, 13:129.
