Description
Prostate Specific Antigen (PSA) is a single-chain glycoprotein secreted by prostate epithelial cells, which belongs to the kininase family, and exists in prostate tissue and semen. PSA can be present alone in free form (fPSA) or in a bound state (cPSA) by binding to α1-antichymotrypsin or α2-macroglobulin. The free form and bound form of PSA together are total PSA (tPSA). PSA has extremely high tissue and organ specificity and is currently the preferred marker for the diagnosis of prostate cancer [1].
HKIG provides monoclonal antibodies for detecting free PSA (fPSA) and total PSA (tPSA), respectively.
Anti tPSA monoclonal antibody
| Catalog No. | Kaff | Subtype | Pairing | Application |
| 1005101 | >109 | Mouse IgG1/κ | Cap. | CLIA, ELISA |
| 1005201 | >109 | Mouse IgG1/κ | Cap./Det. | CLIA, ELISA |
| 1005202 | >109 | Mouse IgG1/κ | Cap./Det. | CLIA, ELISA |
Example of tPSA standard curve (CLIA)
Capture antibody: 1005101, Detection antibody: 1005201. R2>0.99 LoB<0.2ng/mL
Capture antibody: 1005101, Detection antibody: 1005202. R2>0.99 LoB<0.2ng/mL
Reference：
【1】J Clin Oncol. 2003;21(2):383-91.
